orthoeffect on the nitrosation of the 2,3-diphenyl-5(2-methoxyphenyl)pyrrole
Autor: | Vincenzo Sprio, Mirella Ferrugia, Pasquale Agozzino, Leopoldo Ceraulo |
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Rok vydání: | 1990 |
Předmět: | |
Zdroj: | Journal of Heterocyclic Chemistry. 27:255-257 |
ISSN: | 1943-5193 0022-152X |
DOI: | 10.1002/jhet.5570270226 |
Popis: | A comparison of the behaviour on the nitrosation of the isomers 5-(2-methoxyphenyl)- (1a) 5-(3-methoxyphenyl)- (1b) and 5-(4-methoxyphenyl)2,3-diphenylpyrroles (1c) carried out in the usual way with iso-amyl nitrite in a solution of sodium ethoxide in ethanol evidences that 1a is dramatically less reactive with respect to 1b and 1c. The different reactivity was ascribed to the occurrence of a strong hydrogen bond involving pyrrole NH and the ortho-methoxy group. |
Databáze: | OpenAIRE |
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