Stereocontrolled synthesis of tetrahydropyrans via reductive manipulation of 4,10-dioxo-3,5,9,11-tetramethyl-1,7-dioxaspiro[5.5]undecanes

Autor:	Kim F. Albizati, Yun Bo Zhao
Rok vydání:	1993
Předmět:	chemistry.chemical_compound Chemistry Stereochemistry Reductive cleavage Organic Chemistry Drug Discovery Chemical reduction Organic chemistry Stereoselectivity Triol Biochemistry Stereocenter
Zdroj:	Tetrahedron Letters. 34:575-578
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(00)61623-4
Popis:	Stereocontrol in the carbonyl reductions of the titled leads compounds leads to a variety of hydroxylated spiroketals. Reductive cleavage leads to tetrahydropyrans with complete stereocontrol over 7 stereogenic centers.
Databáze:	OpenAIRE
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