An Evans Syndrome Case Expressing Anti-Jka Autoantibody under Condition of Primary IgA Immunodeficiency

Autor: Nobuyuki Yamamoto, Takeshi Sugimoto, Ikuko Kubokawa, Hironobu Minami, Akira Hayakawa, Makoto Hashimoto, Takeshi Mori, Tomoko Yanai, Ayumi Tani, Takeshi Kato, Satoshi Hirase, Ikuyo Hayakawa
Rok vydání: 2015
Předmět:
Zdroj: International Journal of Clinical Medicine. :496-499
ISSN: 2158-2882
2158-284X
DOI: 10.4236/ijcm.2015.67066
Popis: Autoimmune haemolytic anaemia is a haemolytic disease resulting from an autoimmune reaction to the surface of red blood cells. A part of autoantibody is known to react with the blood type antigen. This is the case of a 14 years old female with Evans syndrome in which autoimmune haemolysis may cause from anti-Jka autoantibody reaction. As this case is complicated with primary IgA immunodeficiency syndrome, anti-Jka autoantibody may occur under the condition of primary immunodeficiency status, in which autoantibody production is accelerated. Considering the co-occurrence of autoimmune haemolytic anaemia and primary IgA immunodeficiency syndrome, analysis focusing on specificity for red blood cells antigens will be required in IgA immunodefi-ciency syndrome patients.
Databáze: OpenAIRE