Diagnostic use of fine-needle aspiration cytology and core-needle biopsy in head and neck sarcomas

Autor: Sheppard, Sean C., Borner, Urs, Wartenberg, Martin, Giger, Roland, Nisa Hern��ndez, Llu��s
Rok vydání: 2021
Předmět:
DOI: 10.48350/161394
Popis: The diagnostic role of fine-needle aspiration cytology (FNAC) and core-needle biopsy (CNB) has not been comprehensively assessed in head and neck sarcomas. A systematic review of published cases (1990-2020) was conducted. Diagnostic performance of both FNAC/CNB to determine tumor dignity and histopathological diagnosis was calculated. One hundred and sixty-eight cases were included for which FNAC (n =���156), CNB (n =���8), or both (n =���4) were used. Predominant histologies were skeletal muscle, chondrogenic and vascular sarcomas. FNAC correctly assessed dignity in 76.3% and histology in 45% of cases. Dignity was significantly better for vascular tumors, metastatic and recurrent specimens, and worse for chondrogenic sarcomas. CNB showed a 92% accuracy to identify dignity and 83% for histopathology. FNAC and CNB are useful methods for the diagnosis of head and neck sarcomas, particularly well-suited in the context of recurrent or metastatic disease. The role of CNB remains largely unexplored for this indication.
Databáze: OpenAIRE