Abstract 132: Projections Of Endovascular Therapy-eligible Patients For The Us Population In 2021

Autor: Eva Mistry, Jane C Khoury, Brett Kissela, Dawn O Kleindorfer, Kathleen S Alwell, Adam Jasne, Simona Ferioli, Felipe De Los Rios La Rosa, Elisheva R Coleman, Stacie L Demel, Kyle B Walsh, Sabreena J SLAVIN, Michael Star, Mary Haverbusch, Jason Mackey, Daniel Woo, Mirjam Heldner, Urs M Fischer, Ashutosh Jadhav, Tudor G Jovin, Gregory W Albers, Raul G Nogueira, Pooja Khatri
Rok vydání: 2022
Předmět:
Zdroj: Stroke. 53
ISSN: 1524-4628
0039-2499
DOI: 10.1161/str.53.suppl_1.132
Popis: Introduction: Endovascular (EVT) eligibility estimates using population-based, NIH-funded Greater Cincinnati Northern Kentucky (GCNK) Stroke Study 2010 data have been reported. Given the evolving EVT landscape, we present updated estimates of annual EVT eligibility using the 2015 GCNK epidemiological data and extrapolate to the 2021 US census. We project the potential increase in eligible patients in the US for each possible expanded indication with a randomized trial currently planned/underway. Methods: We ascertained all hospitalized AIS patients ≥18 years old in 2015 using ICD-9 430-436; ICD-10 I60-I67, G45-G46 within GCNK population; all cases were physician-reviewed. Patients presenting within 0-5 hrs of last known well (LKW) were considered EVT eligible if they had a pre-stroke mRS1 (for 0-5 hrs) or ≥2 (for 5-23 hrs), or larger core. Estimates of vessel occlusion and favorable imaging were applied based on literature review and expert opinions. The derived estimates were age, race and sex-adjusted to the 2015 US adult population and extrapolated to 2021 population. Results: Among the 1.3 million total (1.05m adult) GCNK population in 2015, 2741 adults had an ischemic stroke and 2176 had data available for this analysis. A total of 1978 presented within 23 hrs of LKW, and 1233 within 0-5 hrs of LKW. Further results are outlined in the figure. Conclusions: It is estimated 18,484 adult patients in the US in 2021 meet strict EVT eligibility criteria. An estimated 15,699 patients with low NIHSS, 9621 with unfavorable imaging, and 28,107 with pre-stroke disability may become eligible for EVT in the future annually. US stroke systems should be optimized to handle all EVT-eligible stroke patients both now and in the future.
Databáze: OpenAIRE
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