Displaying biofunctionality on materials through templated self-assembly
| Autor: | Dominic W. P. Collis, Clare O'Malley, Kseniya Shuturminska, João Conde, Helena S. Azevedo |
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| Rok vydání: | 2018 |
| Předmět: |
Materials science
Nanoparticle Nanotechnology 02 engineering and technology Adhesion Substrate (printing) 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences 0104 chemical sciences Template Targeted drug delivery Molecule Self-assembly 0210 nano-technology Biomineralization |
| DOI: | 10.1016/b978-0-08-102015-9.00018-6 |
| Popis: | Two-dimensional or three-dimensional templates have been used to drive the self-assembly of molecules onto solid substrates in order to create chemically defined and ordered surfaces. The properties of the substrate can be tuned to manipulate local interactions and direct the assembly of molecules with controlled orientations onto precise positions. Substrates of choice can be flat or patterned 2-D solid surfaces for studying biological processes, such as biomineralization and cellular processes (e.g., adhesion, migration, and differentiation) or 3-D nanoparticles for detecting molecular interactions (diagnostics) and releasing therapeutics (targeted drug delivery). This chapter describes the substrates and methods typically used in templated self-assembly to fabricate biomaterials with high control over presented biofunctionalities, as well as their bio-related applications. |
| Databáze: | OpenAIRE |
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