Śluzak prawego przedsionka u pacjenta z twardziną układową
| Autor: | Marek Zieliński, Beata Trzcińska-Budkiewicz, Małgorzata Peregud-Pogorzelska, Jarosław Kaźmierczak, Marek Brzosko, Maciej Wielusiński |
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| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | Folia Cardiologica. 11:563-566 |
| ISSN: | 2353-7760 2353-7752 |
| DOI: | 10.5603/fc.2016.0116 |
| Popis: | The myxoma makes 80–90% of benign cardiac neoplasms. The first symptom in 50% of patients is an embolism resulting from relocation of tumor fragments or blood clots into the bloodstream. Elevated values of acute phase proteins in these patients are results of non-specific immune response to an antigen causing the disease. Interleukin 6 (IL-6) plays a role in this reaction, modifying inflammatory response by: influence on lymphocyte T differentiation, lymphocyte B to plasmocyte transformation, and stimulation of the liver to produce acute phase proteins. Elevated IL-6 is found in 80% of patients with diagnosed myxoma, which causes it to be an important marker in diagnostic and post-operational monitoring. The role in non-specific inflammatory response played by IL-6 in myxoma and autoimmune disorders was a cause of many diagnostic mistakes. Available literature does not suggest a coincidence of cardiac myxoma and systemic sclerosis. This is why we would like to present a case report, with special regard to correlation between IL-6 values and activity/stage of diagnosed disorders. |
| Databáze: | OpenAIRE |
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