Effect of Luteinizing Hormone (LH) and LH-Releasing Hormone (LHRH) on Testosterone Production In Vivo, in Fetal Rabbit Testis in Late Gestation

Autor:	M. Berger, Georges Veyssiere, C. Jean-Faucher, M. De Turckheim, C. Jean
Rok vydání:	1977
Předmět:	endocrine system Fetus medicine.medical_specialty Chemistry medicine.medical_treatment Stimulation Radioimmunoassay Umbilical vein Andrology Endocrinology Internal medicine Pediatrics Perinatology and Child Health medicine Gestation Luteinizing hormone Saline Testosterone Developmental Biology
Zdroj:	Neonatology. 32:327-330
ISSN:	1661-7819 1661-7800
DOI:	10.1159/000241036
Popis:	Plasma and testicular testosterone were measured by radioimmunoassay in the 29-day-old rabbit fetus receiving an injection of saline solution, LH or LHRH. 30 min following the injection of 5 μg LH into the umbilical vein, testosterone levels were significantly increased by 287% in the plasma and 293% in the testis, compared with controls receiving saline solution. The injection of 2 μg of LHRH under the same conditions significantly increased testicular testosterone by 256% and plasma testosterone by 746%. The results show that the fetal rabbit testis, at the end of gestation, is capable of responding to LH stimulation. The hypophyso-testicular axis is apparently functional at this stage of gestation, as shown by the response to LHRH.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a351b6a7e0920452ff8f6f6e63509ab8 https://doi.org/10.1159/000241036 Zobrazit plný text záznamu