Consumption of orange fermented beverage improves antioxidant status and reduces peroxidation lipid and inflammatory markers in healthy humans
| Autor: | Daniele Del Rio, Isabel Cerrillo, Ángeles Ortega, Franz Martín, María-Soledad Fernández-Pachón, Hada C. Macher, Pedro Mena, Rocío Muñoz-Hernández, Blanca Escudero-López, María-Rosario Rodríguez-Griñolo, Dámaso Hornero-Méndez |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Orange juice 030109 nutrition & dietetics Nutrition and Dietetics Antioxidant Oxygen radical absorbance capacity business.industry Diet therapy Thiobarbituric acid medicine.medical_treatment 030204 cardiovascular system & hematology Lipid peroxidation 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine chemistry TBARS Uric acid Medicine Food science business Agronomy and Crop Science Food Science Biotechnology |
| Zdroj: | Journal of the Science of Food and Agriculture. 98:2777-2786 |
| ISSN: | 0022-5142 |
| Popis: | BACKGROUND: Alcoholic fermentation of fruits has generated novel products with high concentrations of bioactive compounds and moderate alcohol content. The aim of this study was to evaluate the potential effect on cardiovascular risk factors of the regular consumption by healthy humans of a beverage obtained by alcoholic fermentation and pasteurization of orange juice. RESULTS: Thirty healthy volunteers were enrolled in a randomized controlled study. The experimental group (n = 15) drank 500 mL orange beverage (OB) per day for 2 weeks (intervention phase), followed by a 3-week washout phase. Blood samples were collected at baseline (E-T0) and at the end of the intervention (E-T1) and washout (E-T2) phases. Controls (n = 15) did not consume OB during a 2-week period. OB intake significantly increased oxygen radical absorbance capacity (43.9%) and reduced uric acid (−8.9%), catalase (CAT) (−23.2%), thiobarbituric acid reactive substances (TBARS) (−30.2%) and C-reactive protein (−2.1%) (E-T1 vs. E-T0). These effects may represent longer-term benefits, given the decreased uric acid (−8.9%), CAT (−34.6%), TBARS (−48.4%) and oxidized low-density lipoprotein (−23.9%) values recorded after the washout phase (E-T2 vs. E-T0). CONCLUSION: The regular consumption of OB improved antioxidant status and decreased inflammation state, lipid peroxidation and uric acid levels. Thus OB may protect the cardiovascular system in healthy humans and be considered a novel functional beverage. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry |
| Databáze: | OpenAIRE |
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