Neat lipase-catalysed kinetic resolution of racemic 1-phenylethanol and a straightforward modelling of the reaction

Autor:	Zsófia Varga, Ágnes Szécsényi, Ildikó Kmecz, Edit Székely
Rok vydání:	2017
Předmět:	biology Tributyrin 010405 organic chemistry Lipase b Atmospheric temperature range 010402 general chemistry biology.organism_classification 01 natural sciences Biochemistry Catalysis 0104 chemical sciences Kinetic resolution chemistry.chemical_compound chemistry biology.protein Glycerol Organic chemistry Candida antarctica Lipase Biotechnology Initial rate
Zdroj:	Biocatalysis and Biotransformation. 35:427-433
ISSN:	1029-2446 1024-2422
DOI:	10.1080/10242422.2017.1360292
Popis:	Enzymatic kinetic resolution of racemic 1-phenylethanol catalysed by immobilized Candida antarctica lipase B was investigated in a neat system at the temperature range of 30–70 °C. Synthetic triglycerides, namely glycerol triacetate and glycerol tributyrate, were applied as the esterification agents. Both esterification agents were efficient regarding to the enantioselectivity (>1000). Initial rate of reaction and the kinetic constants were influenced by the applied esterification agent significantly. A detailed modelling approach is presented and verified in the temperature range on 30–60 °C for the tributyrin system.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a34a5c97f6d86d3b4e2109dd26b0f39b https://doi.org/10.1080/10242422.2017.1360292 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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