Desulfinylative Pd-catalyzed coupling reaction of arenediazonium salt with aryl sulfinates to give unsymmetrical biaryls
| Autor: | Kishor Eknath Balsane, Jayashree M. Nagarkar, Sitaram Haribhau Gund |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
chemistry.chemical_classification
010405 organic chemistry Aryl Organic Chemistry Iodide chemistry.chemical_element Salt (chemistry) 010402 general chemistry Tetrabutylammonium iodide 01 natural sciences Biochemistry Combinatorial chemistry Coupling reaction 0104 chemical sciences Catalysis chemistry.chemical_compound chemistry Drug Discovery Organic chemistry Inert gas Palladium |
| Zdroj: | Tetrahedron Letters. 58:2936-2939 |
| ISSN: | 0040-4039 |
| DOI: | 10.1016/j.tetlet.2017.06.045 |
| Popis: | An efficient route for the synthesis of unsymmetrical biaryls was developed via palladium catalyzed reaction of arenediazonium salts and aryl sulfinates under inert atmosphere. This synthesis involves cascade processes. Tetrabutylammonium iodide was used as an iodide source for in situ formation of aryl iodide, followed by desulfinylative cross-coupling reaction between aryl sulfinates and aryl iodides. A wide range of biaryls were selectively prepared in one pot from simple substrates in good to excellent yields. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect