A Quantitative Precipitin Study of Porcine Fibrinogen Employing Paired Labels

Autor:	Robert B. Fritz, Sylvester Lassiter, Eugene D. Day
Rok vydání:	1967
Předmět:	Immunology Immunology and Allergy
Zdroj:	The Journal of Immunology. 98:1213-1217
ISSN:	1550-6606 0022-1767
DOI:	10.4049/jimmunol.98.6.1213
Popis:	Summary Globulins from single bleedings of individual rabbits were used to delineate the quantitative precipitin reaction of porcine fibrinogen and its homologous antibody. The use of paired radioactive labels in both antigen and antibody, as an aid in studying the quantitative precipitin reaction, was established. Porcine fibrinogen prepared by different methods yielded antigens with differing immunochemical properties. The effective antigenic valence of one preparation was 27; of another, over 50. Precipitin titrations with one resulted in classically linear Heidelberger plots; with another, in curvilinear departures from the ideal in antibody excess regions.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a31fa74e4e6a3586abbe589091b739f5 https://doi.org/10.4049/jimmunol.98.6.1213 Zobrazit plný text záznamu