Is there any correlation among MKK4 (mitogen-activated protein kinase kinase 4) expression, clinicopathological features, and KRAS/NRAS mutation in colorectal cancer
Autor: | Mutlu Dogan, Servet Guresci, Onder Bozdogan, Oznur Bal, Yusuf Acikgoz, Yakup Ergun, Fahriye Tugba Kos |
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Rok vydání: | 2020 |
Předmět: |
0301 basic medicine
Neuroblastoma RAS viral oncogene homolog Colorectal cancer Biology medicine.disease medicine.disease_cause Pathology and Forensic Medicine Correlation 03 medical and health sciences MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4 030104 developmental biology 0302 clinical medicine 030220 oncology & carcinogenesis RAS Mutation Mutation (genetic algorithm) Genetics Cancer research medicine Molecular Medicine Clinicopathological features KRAS Molecular Biology |
Zdroj: | Expert Review of Molecular Diagnostics. 20:851-859 |
ISSN: | 1744-8352 1473-7159 |
Popis: | We aimed to evaluate the correlation between MKK4 expression and clinicopathological features, KRAS/NRAS mutation in colorectal cancer. MKK4 expression was assessed by immunoreactivity score (IRS).... |
Databáze: | OpenAIRE |
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