Application of Metagenomics Analysis in Carious Lesions:A Review

Autor: Deepika Katyal, Dhakshinamoorthy Malarvizhi, Balasubramaniam Anuradha, Suresh Mitthra
Rok vydání: 2019
Předmět:
Zdroj: Indian Journal of Public Health Research & Development. 10:2131
ISSN: 0976-5506
0976-0245
DOI: 10.37506/v10/i12/2019/ijphrd/192313
Popis: Metagenomics using next generation sequencing technologies has produced bacterial profiles and genomic profiles to study the relationships between microbial diversity, genetic variation, and oral diseases. Several oral metagenomic studies have examined the oral microbiome of periodontal disease and caries. Gene annotations in these studies support the association of specific genes or metabolic pathways with oral health and with specific diseases. The roles of pathogenic species and functions of specific genes in oral disease development have been recognized by metagenomic analysis. This review gives an overview on the interaction between oral microbiomes that determine a state of health or disease.
Databáze: OpenAIRE