Enantioseparations by electrochromatography with packed capillaries

Autor:	William H. Pirkle, Christian Wolf, Ellen M. Derrico, Deniz M. Cavender, Gerard P. Rozing, Patrick L. Spence
Rok vydání:	1997
Předmět:	chemistry.chemical_compound Chromatography Electrochromatography chemistry Organic Chemistry Benzene derivatives Ethanesulfonic acid General Medicine Enantiomer Acetonitrile Chiral stationary phase Biochemistry Analytical Chemistry
Zdroj:	Journal of Chromatography A. 782:175-179
ISSN:	0021-9673
DOI:	10.1016/s0021-9673(97)00863-7
Popis:	( S )-Naproxen-derived and (3 R ,4 S )-Whelk-O chiral stationary phases (CSPs) were immobilized on 3 μm silica supports and packed into 100 μm I.D. fused-silica capillaries. Enantiomers of some neutral analytes representing a variety of different classes of compounds were separated by electrochromatography using 2-(N-morpholino)ethanesulfonic acid modified with acetonitrile as the buffer system. High column efficiency (up to 200 000 plates per meter) and substantial levels of enantioselectivity were obtained in all cases with separations usually being performed in less than 10 min.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a2d13c76e5eb8104c660deeb0f5941ee https://doi.org/10.1016/s0021-9673(97)00863-7 Zobrazit plný text záznamu Full Text from ScienceDirect