Human cyclic neutropenia transferred by allogeneic bone marrow grafting
| Autor: | Stephen J. Forman, Robert B. Rosen, Spruce We, Robert A. Krance, KG Blume, Thomas Hecht, WP Hammond |
|---|---|
| Rok vydání: | 1982 |
| Předmět: |
Pathology
medicine.medical_specialty Bone marrow transplantation Collie business.industry Lymphoblastic Leukemia Immunology Hematopoietic stem cell Cell Biology Hematology medicine.disease Biochemistry Cyclic neutropenia medicine.anatomical_structure Animal model hemic and lymphatic diseases medicine Autogenous bone business |
| Zdroj: | Blood. 60:1263-1266 |
| ISSN: | 1528-0020 0006-4971 |
| DOI: | 10.1182/blood.v60.6.1263.1263 |
| Popis: | Human cyclic neutropenia shows many features in common with the animal model of cyclic neutropenia in grey collie dogs. Until now, however, evidence was lacking that cyclic neutropenia in man as in the dog is caused by a defect in a transplantable hematopoietic stem cell. A patient is presented who, while undergoing bone marrow transplantation as treatment for acute lymphoblastic leukemia in relapse, acquired cyclic neutropenia from her histocompatible sibling donor. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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