An overview on synthetic entries to tetrahydro-β-carbolines

Autor:	Pradipta Maity, Amit Kumar Jana, Debasis Adhikari
Rok vydání:	2019
Předmět:	010405 organic chemistry Feature (computer vision) Chemistry Organic Chemistry Drug Discovery Computational biology 010402 general chemistry 01 natural sciences Biochemistry 0104 chemical sciences
Zdroj:	Tetrahedron. 75:965-1028
ISSN:	0040-4020
DOI:	10.1016/j.tet.2019.01.004
Popis:	The tetrahydro-β-carboline (THBC) nucleus is a predominant feature of a vast array of naturally occurring alkaloids. Most of these alkaloids have been found to exhibit significant biological activities, which promote to develop a plethora of synthetic methods for the construction of THBCs. In this review, we focus on the recent developments and studies related to the synthesis of THBCs including total syntheses of related alkaloids mainly over the period of 2000–2017. In addition, a brief account of some significant THBC alkaloids with their sources and bioactivities is also presented in tabular format.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a2a7aaf897bbe054daff16408b06fad4 https://doi.org/10.1016/j.tet.2019.01.004 Zobrazit plný text záznamu Full Text from ScienceDirect