Case of anti‐Hu antibody‐mediated encephalopathy associated with ovarian cancer
| Autor: | Hiroyuki Shigeta, Shigeki Yamaguchi, Hiroshi Yoshida, Yoichi Kanatsuka, Megumi Furugori |
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| Rok vydání: | 2019 |
| Předmět: |
Oncology
medicine.medical_specialty medicine.diagnostic_test business.industry medicine.medical_treatment Encephalopathy Obstetrics and Gynecology Cancer Magnetic resonance imaging Immunotherapy Status epilepticus Electroencephalography medicine.disease nervous system Internal medicine medicine Levetiracetam medicine.symptom Ovarian cancer business medicine.drug |
| Zdroj: | Journal of Obstetrics and Gynaecology Research. 45:1948-1951 |
| ISSN: | 1447-0756 1341-8076 |
| DOI: | 10.1111/jog.14031 |
| Popis: | The present report describes a case of anti-Hu antibody-mediated encephalopathy associated with ovarian cancer. The patient developed paraneoplastic neurologic syndromes (PNS) during the course of ovarian cancer and showed a symptom of jargon aphasia; diagnosis of PNS was made on the basis of serological and cerebrospinal examination, electroencephalogram (EEG), and magnetic resonance images. EEG initially indicated a condition of non-convulsive status epilepticus; however, levetiracetam administration facilitated complete recovery of this condition. Furthermore, immunotherapy and steroid therapy were very effective and significant improvement was achieved. PNS usually occur before the cancer is identified; however, the possibility of PNS should be considered when neurologic symptoms are noted during the course of oncologic diseases, including ovarian cancer. |
| Databáze: | OpenAIRE |
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