Autor:	I. I. Khegai
Rok vydání:	2002
Předmět:	Mutation medicine.medical_specialty Mutant Biology medicine.disease_cause medicine.disease law.invention Endocrinology Immune system law Internal medicine Diabetes insipidus Genotype Genetics medicine Homologous chromosome Recombinant DNA Gene hormones hormone substitutes and hormone antagonists
Zdroj:	Russian Journal of Genetics. 38:1424-1428
ISSN:	1022-7954
DOI:	10.1023/a:1021600224779
Popis:	The diabetes insipidus mutation is displayed in homozygotes in the form of diabetes insipidus with water consumption from 30 to 100% of body weight per day. We developed two inbred sublines of the di/di Brattleboro rats as well as the recombinant inbred subline by integrating genes of August rats into the di/di mutant genome. Changes in the genetic background proved to have no effect on the quantitative parameters of the diabetes insipidus. The intensity of the secondary immune response and the content of tropomyosin in the medulla of the rat kidney can serve as additional marker traits of the di/di genotype.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a2a16adfd790b5be410107a8beec1272 https://doi.org/10.1023/a:1021600224779 Zobrazit plný text záznamu Full text from SpringerLink