ChemInform Abstract: Synthesis, Dimroth Rearrangement and Blood Platelet Disaggregation Property of Pyrimido[4′,5′:4,5]selenolo[2,3-b]quinolines: A New Class of Condensed Quinoline

Autor:	T. P. Krishnakantha, S. K. Nandeeshaiah, Sarvottam Y. Ambekar
Rok vydání:	2010
Předmět:	Diazine chemistry.chemical_compound Pyrimidine Platelet aggregation Chemistry Stereochemistry Platelet disaggregation Quinoline General Medicine Dimroth rearrangement
Zdroj:	ChemInform. 30
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.199918129
Popis:	Compounds containing 4-aminoselenolo[3,2-d] pyrimidine in a novel tetracyclic condensed quinoline system viz. pyrimido[4',5':4,5]selenolo [2,3-b]quinoline have been synthesized. Dimroth rearrangement of this new condensed diazine system is studied. Biological study shows that while all compounds are active against collagen induced blood platelet aggregation, they are found to be inactive against ADP induced blood platelet aggregation.
Databáze:	OpenAIRE
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