Lipid profile in children with Nephrotic syndrome
| Autor: | Sharad Agarkhedkar, Renuka Jadhav, Suhas Sodal, Anshuman Singh, Shradha Salunkhe, Sanjay Chavan |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Ldl cholesterol
medicine.medical_specialty Triglyceride medicine.diagnostic_test business.industry Cholesterol medicine.medical_treatment 030232 urology & nephrology medicine.disease Gastroenterology Steroid 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine chemistry 030220 oncology & carcinogenesis Internal medicine Hyperlipidemia Medicine lipids (amino acids peptides and proteins) Hypoalbuminemia business Lipid profile Nephrotic syndrome |
| Zdroj: | Pediatric Review: International Journal of Pediatric Research. 5:314-319 |
| ISSN: | 2349-3267 2349-5499 |
| DOI: | 10.17511/ijpr.2018.i06.03 |
| Popis: | Background: To study the derangement of serum lipid profile in children 2 to 12 years with nephrotic syndrome. Methods: 50 children 2 to 12 years with nephrotic syndrome were identified. Patients were classified as remission, relapse and newly diagnosed. Lipid Profile was measured. Patients were followed-up after 4 weeks of steroid therapy. Results: Out of all the 50 subjects screened, 25 (50%) subjects had high total cholesterol, 26 (52%) had high triglyceride, 8 (16%) had abnormal HDL cholesterol and 25 (50%) had high LDL cholesterol. After 4 weeks of steroid therapy though there was significant reduction in lipid components. Conclusion: Our study shows that in nephrotic syndrome, there is generalised hyperlipidemia and hypoalbuminemia. Serum cholesterol, triglycerides and LDL cholesterol were deranged in almost all subjects. In cases in relapse after 4 weeks of steroid therapy there is persistent raised total cholesterol, triglycerides and LDL cholesterol, which may predispose to the development of atherosclerosis in near future. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|