Expectant management in nulliparous term pregnant women with premature rupture of membranes and an unripe cervix

Autor:	M. Hammarström, L. Granström, B. Moberger, R. Hjertberg, A. Berg, E. Nordlander
Rok vydání:	1995
Předmět:	Gynecology Pessary medicine.medical_specialty business.industry Incidence (epidemiology) Obstetrics and Gynecology medicine.disease Group B medicine.anatomical_structure Unripe cervix medicine Prostaglandin E2 business Cervix Premature rupture of membranes Expectant management medicine.drug
Zdroj:	Journal of Obstetrics and Gynaecology. 15:366-372
ISSN:	1364-6893 0144-3615
DOI:	10.3109/01443619509009162
Popis:	SummaryIn total 181 nulliparous term pregnant women with premature rupture of membranes, no uterine contractions and an unripe cervix were allocated at random to labour induction after 12 hours (Group A) or 24 hours (Group B). As long as the cervix remained unfavourable (cervical score ≤5) a pessary containing 3 mg of prostaglandin E2 was applied vaginally in the posterior fornix every 12 hours starting 12 or 24 hours after premature rupture of membranes. In Group A, 72 (75 per cent) required induction of labour while 46 (50 per cent) in Group B started their labour spontaneously (P < 0.05). The need for prostaglandin E2 was more frequent in Group A compared with Group B (P < 0.05). The number of instrumental deliveries did not differ. Maternal complications and the neonatal infectious morbidity was the same in the two groups. We conclude that expectant management for 24 hours results in a high incidence of spontaneous ripening of the cervix combined with spontaneous onset of labour with no disadvantage w...
Databáze:	OpenAIRE
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