Synthesis of new stable analogues of prostacyclin: (±)-6a-oxo-6,9-metrano-15-hydroxyprosta-5,13-dienoic acids

Autor:	T. W. Hart, H. J. Mason, C.J. Hardy, Caton Michael P L, Clive W. Bird, E.C.J. Coffee, H.I. Butler
Rok vydání:	1985
Předmět:	chemistry.chemical_classification Ketone Bicyclic molecule Platelet aggregation Stereochemistry Organic Chemistry Prostacyclin Biochemistry chemistry Drug Discovery Wittig reaction medicine Organic chemistry lipids (amino acids peptides and proteins) Aliphatic compound medicine.drug
Zdroj:	Tetrahedron Letters. 26:4101-4104
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(00)89303-x
Popis:	The synthesis is described of (±)-6a-oxo-6,9-methano-15-hydroxyprosta-5,13-dienoic acids as stable analogues of prostacyclin with blood platelet aggregation inhibiting activity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a263ca4dbb665d2099e7f5a8c75da9fa https://doi.org/10.1016/s0040-4039(00)89303-x Zobrazit plný text záznamu