Adrenergic control of production of humoral regulators of hemopoiesis in cytostatic myelodepression

Autor: A. M. Dygai, S. G. Aksinenko, Gol'dberg Ed, B. Yu. Gumilevskii, Igor A. Khlusov
Rok vydání: 1995
Předmět:
Zdroj: Bulletin of Experimental Biology and Medicine. 119:127-131
ISSN: 1573-8221
0007-4888
DOI: 10.1007/bf02445856
Popis: It is established that the sympathetic nervous system controls the production of humoral regulators of hemopoiesis by bone marrow cells forming a hemopoiesis-inducing microenvironment in mice treated with 5-fluorouracil. The suppressive effect of catecholamines on the erythropoietic and colony-stimulating activities of the adhesive, nonadhesive, as well as the whole fraction of the bone marrow is shown using catecholamines and ganglioblocker in the period of restoration of hemopoiesis after cytostatic treatment.
Databáze: OpenAIRE