Les récepteurs à Epidermal Growth Factor (REGF), une nouvelle cible thérapeutique
| Autor: | A Dufresne, Xavier Pivot, M Gainet, E Guardiola |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Cetuximab
biology business.industry Growth factor medicine.medical_treatment Gefitinib Oncology Growth factor receptor Epidermal growth factor Monoclonal medicine Cancer research biology.protein Panitumumab Radiology Nuclear Medicine and imaging Epidermal growth factor receptor business medicine.drug |
| Zdroj: | Cancer/Radiothérapie. 7:195-199 |
| ISSN: | 1278-3218 |
| DOI: | 10.1016/s1278-3218(03)00019-2 |
| Popis: | Epidermal Growth Factor receptor (EGFR) are a key factor for the tumoral proliferation and its tumoral over expression appears to be a powerful prognosis factor. Currently, 2 types of treatments are targeting EGFR: a monoclonal antibodies anti-EGFR and a specific inhibitors of the EGFR tyrosine kinase. The administration of these compound alone or in combination with chemotherapy gives some promising results. These targets as anti-cancer therapy had emerged to be a new perspective for oncology. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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