Modulation of Respiration by Brain Hypoxia

Autor: Q. P. Yu, J. E. Melton, Norman H. Edelman, J. A. Neubauer, L. O. Chae
Rok vydání: 1992
Předmět:
Zdroj: Control of Breathing and Its Modeling Perspective ISBN: 9781475798494
DOI: 10.1007/978-1-4757-9847-0_54
Popis: The dual nature of hypoxic modulation of central respiratory activity is best appreciated in the sino-aortic deafferented, anesthetized animal during progressive reductions in the arterial oxygen content.1 Figure 1 illustrates these two distinct central respiratory responses to brain hypoxia and their different oxygen thresholds; respiratory depression, which is manifested with even modest reductions in oxygenation, and respiratory excitation (gasping), which occurs only with severe reductions in the arterial oxygen content (to values less than 20%).
Databáze: OpenAIRE
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