Correlation of late gadolinium enhancement MRI and quantitative T2 measurement in cardiac sarcoidosis

Autor: Kim A. Connelly, Katherine Safka, Idan Roifman, Meyer Balter, Yuesong Yang, Mohammad I. Zia, Alexander Dick, John J. Graham, Graham A. Wright
Rok vydání: 2013
Předmět:
Zdroj: Journal of Magnetic Resonance Imaging. 39:609-616
ISSN: 1053-1807
DOI: 10.1002/jmri.24196
Popis: Purpose To investigate the potentially improved detection and quantification of cardiac involvement using novel late-gadolinium-enhancement (LGE) cardiac magnetic resonance imaging (MRI) and quantitative T2 measurement to achieve better myocardial tissue characterization in systemic sarcoidosis. Materials and Methods Twenty-eight patients with systemic sarcoidosis underwent a cardiac magnetic resonance imaging (CMR) study on a 1.5T system. Precontrast CMR included left ventricular (LV) and right ventricular (RV) function and quantitative T2 measurement. Postcontrast LGE-MRI included inversion-recovery fast-gradient-echo (IR-FGRE) and multicontrast late-enhancement imaging (MCLE). Results LV functional parameters were normal in all patients (LVEF = 61.2 ± 8.5%) including with cardiac involvement (LVEF = 59.4 ± 12.1%) and without (LVEF = 61.7 ± 7.5%) while the average RV function was comparatively decreased (RVEF = 48.0 ± 6.6%, P
Databáze: OpenAIRE