Stability of bone marrow stromal cells to low temperatures depending on degree of differentiation

Autor: G. G. Prokhorov, Pinaev Gp, Miralda I. Blinova, M. Raydan, N. S. Nikolaenko, N. A. Shubin
Rok vydání: 2011
Předmět:
Zdroj: Cell and Tissue Biology. 5:294-299
ISSN: 1990-5203
1990-519X
DOI: 10.1134/s1990519x11030084
Popis: Based on a previous study of the stability of a heterogenous population of keratinocytes against cold depending on their degree of differentiation, we studied in vitro the stability of rat bone marrow stem cells (BMSCs) against cold before and after their differentiation in the adipogenic or osteogenic direction. It was shown that, after the induction of differentiation, BMSCs were least stable against the action of low temperatures than the undifferentiated cells. The obtained data can serve as a basis for the further study of processes and mechanisms that affect the stability of BMSCs against cold depending on their degree of differentiation.
Databáze: OpenAIRE