High-Pressure-Promoted and Facially Selective Diels–Alder Reactions of Enzymatically Derived cis-1,2-Dihydrocatechols and Their Acetonide Derivatives: Enantiodivergent Routes to Homochiral and Polyfunctionalized Bicyclo[2.2.2]octenes

Autor:	Anthony C. Willis, Yinglai Teng, Roberto Cammi, Li-Juan Yu, Michelle L. Coote, Bo Chen, Scott G. Stewart, Martin G. Banwell, Gwion J. Harfoot, Kenneth J. McRae
Rok vydání:	2020
Předmět:	Bicyclic molecule 010405 organic chemistry Organic Chemistry 010402 general chemistry 01 natural sciences Toluene Acetonide 0104 chemical sciences chemistry.chemical_compound chemistry Biotransformation Chlorobenzene High pressure Diels alder Organic chemistry
Zdroj:	The Journal of Organic Chemistry. 85:13080-13095
ISSN:	1520-6904 0022-3263
DOI:	10.1021/acs.joc.0c01767
Popis:	cis-1,2-Dihydrocatechols 5 (X = Me and Cl), which are available in the homochiral form through the whole-cell biotransformation of toluene and chlorobenzene, respectively, undergo Diels–Alder cyclo...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a233250bf505fa7f10c193785e832bd8 https://doi.org/10.1021/acs.joc.0c01767 Zobrazit plný text záznamu