Development of Breathing Rat-Lung Models for Particulate Deposition Studies

Autor: Frederick J. Miller, Judith A. Graham, Amit L. Patra
Rok vydání: 1982
Předmět:
Zdroj: Instrumentation Science & Technology. 12:135-149
ISSN: 1525-6030
1073-9149
DOI: 10.1080/10739148208543553
Popis: Techniques have been developed for casting both solid and hollow lung models from rat-lung specimens. To make a solid model, an air line at a positive pressure of 25 cm of water was connected to the trachea to air-dry lungs which had been removed surgically from the animal. Using the lost wax technique, a hollow cast of the airways and the nasopharynx was made. A mechanical breathing system, capable of simulating different breathing patterns, was developed.
Databáze: OpenAIRE