Development of Breathing Rat-Lung Models for Particulate Deposition Studies
Autor: | Frederick J. Miller, Judith A. Graham, Amit L. Patra |
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Rok vydání: | 1982 |
Předmět: |
Lung
Materials science General Chemical Engineering digestive oral and skin physiology Positive pressure Breathing system respiratory system Particulates respiratory tract diseases medicine.anatomical_structure Breathing pattern Casting (metalworking) Breathing medicine Deposition (phase transition) Instrumentation General Environmental Science Biomedical engineering |
Zdroj: | Instrumentation Science & Technology. 12:135-149 |
ISSN: | 1525-6030 1073-9149 |
DOI: | 10.1080/10739148208543553 |
Popis: | Techniques have been developed for casting both solid and hollow lung models from rat-lung specimens. To make a solid model, an air line at a positive pressure of 25 cm of water was connected to the trachea to air-dry lungs which had been removed surgically from the animal. Using the lost wax technique, a hollow cast of the airways and the nasopharynx was made. A mechanical breathing system, capable of simulating different breathing patterns, was developed. |
Databáze: | OpenAIRE |
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