Nucleotide sequence of a new Fc gamma receptor IIIB allele that codes for a neutrophil antigen

Autor:	H. Niihara, Takeo Juji, K. Shimano, Koki Fujiwara, Eiko Shimada, Shigeki Mitsunaga, Yoshihisa Watanabe, Kenji Tadokoro
Rok vydání:	2000
Předmět:	chemistry.chemical_classification Fc gamma receptor IIIb medicine.drug_class Immunology Nucleic acid sequence General Medicine Biology FCGR3B Monoclonal antibody Biochemistry Molecular biology chemistry Antigen Genetics medicine Immunology and Allergy Nucleotide Allele Gene
Zdroj:	Tissue Antigens. 56:272-275
ISSN:	0001-2815
DOI:	10.1034/j.1399-0039.2000.560310.x
Popis:	A new allele of the human neutrophil antigen (HNA) system (tentatively called NA2M) was discovered and its nucleotide sequence was determined. NA2M differs in a single nucleotide (193GA) from FCGR3B*2(NA2), resulting in an amino acid change (54GluLys). The frequency of the NA2M gene in the Japanese population was estimated to be 0.008. Granulocytes of individuals possessing NA2M reacted with HNA-1b(NA2)-specific monoclonal antibody (TAG2) in the GIFT assay ( Note).
Databáze:	OpenAIRE
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