| Autor: |
Hua Lu, Rujing Zhang, Nathan P. Gabrielson, Nan Zheng, Lichen Yin, Ziyuan Song, Jianjun Cheng, Kyung Mo Kim, Yao Lin, Haoyu Tang |
| Rok vydání: |
2014 |
| Předmět: |
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| Zdroj: |
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology. 7:98-110 |
| ISSN: |
1939-5116 |
| DOI: |
10.1002/wnan.1307 |
| Popis: |
The advent of polymeric materials has significantly promoted the development and rapid growth of various technologies in biomedical applications, such as tissue engineering and controlled drug and gene delivery. Water-soluble polypeptides bearing functional side chains and adopting stable secondary structures are a new class of functional polymeric materials of potentially broad applications in medicine and biotechnology. In this article, we summarize our recent effort on the design and synthesis of the water-soluble �� -helical ionic polypeptides originally developed in our laboratory and highlight their applications in cell membrane penetration and nonviral gene/small interfering RNA (siRNA) delivery. © 2014 Wiley |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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