Synthesis of Chiral Pyridyl Alcohols Using a Two-Step Catalytic Approach

Autor: Andrey Gutnov, Marko Hapke, Reinhard Karge, Dmitry Redkin, Christine Fischer, Barbara Heller, Werner Bonrath
Rok vydání: 2008
Předmět:
Zdroj: Synthesis. 2008:69-74
ISSN: 1437-210X
0039-7881
DOI: 10.1055/s-2007-990903
Popis: Chiral pyridyl alcohols have been prepared by developing a two-step approach that uses the asymmetric cyanation of aldehydes- to give cyanohydrins and subsequent [2+2+2]-cyclotri-merization reaction with acetylene.
Databáze: OpenAIRE