A novel and efficient synthesis of 9-(2-hydroxyethyl)-7,11-dioxaspiro[5,5] undecane useful in the preparation of antiviral acyclonucleosides

Autor:	P. Srinagesh Kumar, K. Srinivas, C. K. Snehalatha Nair, M. Pardhasaradhi
Rok vydání:	1998
Předmět:	chemistry.chemical_compound Chemistry Organic Chemistry Drug Discovery Organic chemistry Ring (chemistry) Undecane Biochemistry Combinatorial chemistry Hydroformylation Catalysis
Zdroj:	Tetrahedron Letters. 39:7411-7412
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(98)01609-8
Popis:	An efficient four step route for the synthesis of 9-(2-hydroxyethyl)-7,11-dioxaspiro[5,5] undecane, an intermediate in the preparation of antiviral acyclonucleosides is described. The key transformations, ketalisation, hydroformylation and ring transformation are achieved through catalytic reactions.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a1f7ecda4ededa0e7a87cb268f010d13 https://doi.org/10.1016/s0040-4039(98)01609-8 Zobrazit plný text záznamu Full Text from ScienceDirect