Incidencia del carcinoma transicional del tracto urinario superior en España
| Autor: | T. Fernandez Aparicio, J.A. Galan Llopis, R. Cansino Alcaide, D. Pérez Fentes, M. Cepeda Delgado, J.L. Alvarez-Ossorio, D. Perez Fentes, Cepeda Delgado, M.I. Osman García, C. Hernandez Fernández, S. Moreno Sorribas, J. Extramiana Cameno, R. Espilez Ortiz, J.L. Moyano Calvo, A. Jalón Monzón, A. Rivero Guerra, M. Chaves Santamaria, A. Fernández Alcalde, P. Guzman Martínez-Valls, A. Rivero Cardenes, A.M. Iturregui del Pozo, A. Carrion Puig, M.I. Rodriguez Cruz, Juan Ramon Torrecilla García-Ripoll, K. Severino Ortiz de Zarate, D. Hernandez Alcaraz, J.L. Gutierrez Baños, J.I. Monzó Gardiner, A. Amador Robayna, C. Blazquez Vallejo, P. Jimenez Marrero, F. Lozano Uruñuela, L. Calahorra Fernandez, R. Campanario Perez, J. Moreno Jiménez, A. Husillos Alonso, J.A. Campos Sañudo |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
medicine.diagnostic_test business.industry Urology Incidence (epidemiology) Mortality rate 030232 urology & nephrology 03 medical and health sciences 0302 clinical medicine Upper tract Internal medicine Epidemiology medicine Electronic data Ureteroscopy business Urothelial carcinoma Upper urinary tract |
| Zdroj: | Actas Urológicas Españolas. 44:512-518 |
| ISSN: | 0210-4806 |
| DOI: | 10.1016/j.acuro.2020.03.007 |
| Popis: | Introduction and objectives: The incidence of upper urinary tract tumors is currently unknown. The aim of this study is to determine the real incidence of upper tract urothelial carcinoma (UTUC) in Spain. Material and methods: A descriptive, prospective and multicenter epidemiological study was conducted in 31 Spanish facilities by means of the Platform for Multicenter Studies of the Spanish Association of Urology. Recruitment was opened from May 1st, 2017 to April 30th, 2018. The original database was exported directly from the electronic Data Collection Logbook on December 15th, 2018, with a total of 404 cases registered (402 valid cases after depuration). Statistical analysis was performed using IBM SPSS software v 23 and EPIDAT v 3.4. Results: The incidence adjusted to Spanish population from raw data was 3.27 cases per 100.000 inhabitants per year (2.93 – 3.61 95% CI) and 3,3 cases per 100.000 inhabitants per year (2.96-3.66 95%CI) when adjusted to European population by age. The mean age at diagnosis was 70 years, and 77% of patients were male. Thirty-four percent of patients had an incidental diagnosis. Tumors were most commonly located in the pyelocalyceal system (54%), followed by the distal ureter (22%). Prior ureteroscopy was performed in 114 patients: this technique modified the subsequent treatment indication in 58% of cases. Radical nephroureterectomy was performed in 311 patients. Kidney-sparing surgery was the elected treatment in 76 patients (20%). Complications were found in 69% of cases, most of them classified as Clavien 1 and 2 (86% of all complications). Postoperative mortality rate was 1.7%. Conclusions: UTUC adjusted incidence rate in Spain is 3.27 and 3.3 in Europe. Prior URS modified the treatment indication in 18% of patients. We found a 69% complication rate and a 1.7% mortality rate. |
| Databáze: | OpenAIRE |
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