Kinetics and mechanism of the oxidation of some neutral and acidic α-amino acids by tetrabutylammonium tribromide

Autor: Kalyan K. Banerji, Pradeep K. Sharma, Raghvendra Shukla
Rok vydání: 2004
Předmět:
Zdroj: Journal of Chemical Sciences. 116:101-106
ISSN: 0973-7103
0253-4134
DOI: 10.1007/bf02708202
Popis: The oxidation of eleven amino acids by tetrabutylammonium tribromide (TBATB) in aqueous acetic acid results in the formation of the corresponding carbonyl compounds and ammonia. The reaction is first order with respect to TBATB. Michaelis-Menten type kinetics is observed with some of the amino acids while others exhibit second-order dependence. It failed to induce polymerization of acrylonitrile. The effect of solvent composition indicate that the rate of reaction increases with increase in the polarity of the medium. Addition of tetrabutylammonium chloride has no effect on the rate of oxidation. Addition of bromide ion causes decrease in the oxidation rate but only to a limiting value. The reaction is susceptible to both polar and steric effects of the substituents. A suitable mechanism has been proposed
Databáze: OpenAIRE