Production of Proteinase with Plasmin-Like and Prekallikrein Activating Activity by the Micromycete Aspergillus terreus
| Autor: | I. B. Kotova, V. G. Kreier, N. A. Baranova, A. A. Osmolovskiy, E. S. Zvonareva, N. S. Egorov |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
biology Chemistry Plasmin Prekallikrein Fibrinogen biology.organism_classification Applied Microbiology and Biotechnology Biochemistry Fibrin 03 medical and health sciences 030104 developmental biology Extracellular biology.protein medicine Secretion Fermentation Aspergillus terreus medicine.drug |
| Zdroj: | Applied Biochemistry and Microbiology. 54:206-210 |
| ISSN: | 1608-3024 0003-6838 |
| Popis: | The effect of nitrogen sources in the fermentation medium and the cultivation conditions on the production of proteinases with plasmin-like and prekallikrein activation activity by micromycete Aspergillus terreus 2 was investigated. The highest secretion of proteinases was achieved when the micromycete was cultivated on a medium containing both amine- and mineral nitrogen sources at an initial pH of 5.5 and at 28°С. It was established that the extracellular micromycete proteinases are equally capable of hydrolyzing fibrin and fibrinogen. |
| Databáze: | OpenAIRE |
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