Assembly and disassembly of mammalian Chromosome pellicle

Autor:	Luji Shi, Zumei Ni, Little Je
Rok vydání:	1992
Předmět:	Nucleolus Cell Biology Biology Molecular biology 3T3 cells Cell biology medicine.anatomical_structure Antigen medicine Telophase Prometaphase Molecular Biology Metaphase Mitosis
Zdroj:	Cell Research. 2:195-201
ISSN:	1748-7838 1001-0602
DOI:	10.1038/cr.1992.18
Popis:	By means of indirect double immunofluorescent staining,the coordination of PI antigen and perichromonucleolin(PCN),the constituent of nuclear periphery and nucleolus respectively,in the assembly and disassembly of chromosome pellicle during mitosis was studied.It was found that in 3T3 cells,during mitosis PI antigen began to coat the condensing chromosome surface earlier than PCN did.However,both of them completed their coating on chromosome at approximately the same stage of mitosis,prometaphase metaphase,The dissociation of mitosis,Prometaphase metaphase.The dissociation of PI antigen from chromosome pellicle to participate the formation of nuclear periphery took place also ahead of that of PCN,At early telophase PI antigen had been extensively involved in the formation of nuclear periphery,while PCN remained in association with the surface of decondensing chromosomes.At late telophase,when PI antigen was localized in an fairly well formed nuclear periphery,PCN was in a stage of forming prenucleolar bodies.
Databáze:	OpenAIRE
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