Silica-Supported Gold Nanoparticles Catalyzed One-Pot, Tandem Aerobic Oxidative Cyclization Reaction for Nitrogen-Containing Polyheterocyclic Compounds

Autor:	Chi-Ming Che, Kar-Yee Lam, Yungen Liu, Man-Ho So, Chi-Ming Ho
Rok vydání:	2010
Předmět:	Tandem Organic Chemistry chemistry.chemical_element Nanoparticle Heterogeneous catalysis Nitrogen Oxygen Catalysis Inorganic Chemistry chemistry Colloidal gold Organic chemistry Centrifugation Physical and Theoretical Chemistry
Zdroj:	ChemCatChem. 3:386-393
ISSN:	1867-3880
DOI:	10.1002/cctc.201000312
Popis:	A silica-supported gold nanoparticle catalyst AuNPs/SiO2 (A) has been prepared by deposition of in situ synthesized gold nanoparticles (AuNPs) onto the surface of silica. A simple method that uses A as the catalyst and oxygen as the oxidant is effective for oxidative cyclization of anilines with aldehydes to form quinolines in a one-pot reaction (20 examples; product yields up to 95 %). The “AuNPs/SiO2+O2” protocol is applicable to the synthesis of nitrogen-containing polyheterocyclic compounds in good to excellent product yields by using bulky polycyclic anilines as the starting materials (10 examples; product yields up to 96 %). The A catalyst can be easily recovered by centrifugation and reused for seven consecutive runs without significant loss of catalytic activity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a1cf6339c684fcbb946bc835998bb4e3 https://doi.org/10.1002/cctc.201000312 Zobrazit plný text záznamu Plný text