Predicting Adverse Outcomes in Healthy Aging Community-Dwelling Early-Old Adults with the Timed Up and Go Test
| Autor: | Magdalena Janusz-Jenczeń, Katarzyna Antoniak-Sobczak, Agnieszka Batko-Szwaczka, Krzysztof Wilczynski, Jan Duława, Jacek Durmała, Joanna Szołtysek, Jan Szewieczek, Karolina Szuster-Kowolik, Iwona Włodarczyk, Bartosz Wnuk, Beata Hornik |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Activities of daily living business.industry Incidence (epidemiology) Poison control General Medicine Timed Up and Go test Logistic regression Confidence interval 03 medical and health sciences 0302 clinical medicine Internal medicine Cohort Injury prevention medicine 030212 general & internal medicine Geriatrics and Gerontology business human activities 030217 neurology & neurosurgery |
| Zdroj: | Clinical Interventions in Aging. 15:1263-1270 |
| ISSN: | 1178-1998 |
| Popis: | Background Simple, easy-to-perform, safe and cost-effective methods for the prediction of adverse outcomes in older adults are essential for the identification of patients who are most likely to benefit from early preventive interventions. Methods The study included 160 community-dwelling individuals aged 60-74 years, with 44.4% women. A comprehensive geriatric assessment was performed in all participants. Bioimpedance body composition analysis included 149 subjects. Among other tests, functional assessment included the Barthel Index of Activities of Daily Living (Barthel Index), Mini-Mental State Examination (MMSE), Timed Up and Go (TUG) and Fried frailty phenotype. Follow-up by telephone was made after at least 365 days. The composite endpoint (CE) included fall, hospitalization, institutionalization and death. Results Cohort characteristics: age 66.8±4.2 years (mean±SD), 3.81±2.23 diseases, 4.29±3.60 medications or supplements, and good functional status (MMSE 29.0±1.5, Barthel Index 98.1±8.2, prevalence of Fried frailty phenotype 2.5%). During one-year follow-up, 34 subjects (21.3%; 95% confidence interval [CI] =14.9-27.6%) experienced CE: hospitalizations (13.8%; 95% CI=8.41-19.1), falls (9.38%; 95% CI=4.86-13.9), death (0.63%; 95% CI=0-1.85) and no institutionalization. A higher probability of CE was associated with age ≥70 years (P=0.018), taking any medication or supplements (P=0.007), usual pace gait speed ≤0.8 m/s (P=0.028) and TUG >9 s (P |
| Databáze: | OpenAIRE |
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