Popis: |
Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most used pharmaceuticals in the human and veterinary medicine, and it has been demonstrated that their widespread consumption all over the world has led to their ubiquitous occurrence in water environment. Nowadays, there exist strong evidence about the presence of different NSAIDs, such as diclofenac, naproxen, ketorolac, ibuprofen, ketoprofen, and salicylic acid, among others, which are found in concentrations in the range of ng/L to mg/L on different water bodies. Besides, the toxicological effects that NSAIDs cause in aquatic organisms have been evaluated by working groups all over the world. Thus, the aim of this review is to provide a detailed overview about the presence of NSAIDs in aquatic environmental, in particular to summarizing the main toxicological effects on living organisms and occurrence in water bodies that has been documented. |