Effect of Tetracycline on Reproductive Functions in Male Albino Rats
| Autor: | Oyedeji K. O |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Kidney
medicine.medical_specialty medicine.diagnostic_test biology Tetracycline business.industry media_common.quotation_subject Semen analysis biology.organism_classification Streptomyces Sperm medicine.anatomical_structure Endocrinology Distilled water Internal medicine medicine Reproduction business Testosterone medicine.drug media_common |
| Zdroj: | IOSR Journal of Dental and Medical Sciences. 3:55-60 |
| ISSN: | 2279-0853 2279-0861 |
| DOI: | 10.9790/0853-0355560 |
| Popis: | Tetracycline is a broad spectrum antibiotic produced by Streptomyces genus actinobacteria, indicated for use against many bacterial infections. Several studies have reported its effect on protein synthesis and teratogenicity but there is scanty information on its effect on male reproduction. This study was design to investigate the effect of this drug on serum testosterone level and sperm characteristic in male albino rats. Tetracycline (25 mg/kg BW) was administered for 30 days for andrological studies. Distilled water (0.5 ml) serves as the control. Serum testosterone level was assayed using Enzyme-Link Immunosorbent Assay (ELISA) and semen analysis was done microscopically, histological analysis of the testis, kidney and liver were also carried out. Data were analysed using the student’s t-Test at p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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