Synthesis of 2-Aryl Benzothiazoles via K2S2O8-Mediated Oxidative Condensation of Benzothiazoles with Benzylamines

Autor:	Jidan Liu, Ji-Cheng Shi, Anwei Wang, Hua Wang, Ze Tan, Qingwen Gui, Zhiyong Yang, Xiang Chen
Rok vydání:	2013
Předmět:	chemistry.chemical_compound Oxidative cyclization chemistry Aryl Organic Chemistry Condensation Oxidative phosphorylation Combinatorial chemistry Catalysis
Zdroj:	Synlett. 24:1549-1554
ISSN:	1437-2096 0936-5214
DOI:	10.1055/s-0033-1339193
Popis:	A novel way to synthesize 2-arylbenzothiazoles is described. Reactions of benzothiazoles with diverse benzylamines in the presence of K2S2O8 and KOt-Bu in DMSO–H2O afforded the desired 2-arylbenzothiazoles in good yields. It is notable that no transition-metal catalyst is needed in this reaction. Compared with other known methods, this method of synthesizing 2-arylbenzothiazoles can be advantageous in cases where substituted benzothiazoles and benzylamines are readily available.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a1af583a4b6376be42bfd0898f6e2eac https://doi.org/10.1055/s-0033-1339193 Zobrazit plný text záznamu