Immunologic activity of human lymph cells in the blast transformation reaction

Autor:	D. K. Bashirova, F. A. Davletkil'deev, M. V. Lagutina, O. S. Kochnev
Rok vydání:	1980
Předmět:	Pathology medicine.medical_specialty Blast transformation General Medicine Biology Jaundice General Biochemistry Genetics and Molecular Biology Thoracic duct medicine.anatomical_structure Lymphatic system Lymph drainage Immunology medicine Lymph Bacterial antigen medicine.symptom
Zdroj:	Bulletin of Experimental Biology and Medicine. 89:42-44
ISSN:	1573-8221 0007-4888
DOI:	10.1007/bf00835497
Popis:	The immunologic activity of lymph cells obtained in the course of therapeutic drainage of the thoracic duct was studied in 14 patients with subhepatic jaundice of varied genesis. The blast transformation of lymphocytes reaction showed that lymphocytes from lymph are capable of blast formation when exposed to the action of phytohemagglutinin, antilymphocytic γ-globulin, and certain bacterial antigens. The highest intensity of the reaction was found in cultures of lymph lymphocytes taken for these purposes on the 2nd–3rd days after the beginning of lymph drainage. In the course of lymphorrhea the ability of stimulated lymph cells to undergo blast formation is reduced. In the period of lymph drainage, no blast formation takes place in stimulated cultures of patients' blood cells. The majority of antigen-sensitive lymphocytes is thus in a reserve state in the lymphoid tissue of the body.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a1a3f8bc4be69e80631035f6e47cdd38 https://doi.org/10.1007/bf00835497 Zobrazit plný text záznamu Full text from SpringerLink