Microfluidic synthesis of monodisperse PDMS microbeads as discrete oxygen sensors
Autor: | Srinivasa R. Raghavan, Don L. DeVoe, Samuel P. Forry, Peter C. Thomas, Kunqiang Jiang |
---|---|
Rok vydání: | 2012 |
Předmět: | |
Zdroj: | Soft Matter. 8:923-926 |
ISSN: | 1744-6848 1744-683X |
Popis: | We describe the creation of monodisperse microbeads of polydimethylsiloxane (PDMS) via a microfluidic approach. Using a flow-focusing configuration, a PDMS precursor solution is dispersed into microdroplets within an aqueous continuous phase. These droplets are collected and thermally cured off-chip into solid microbeads. Our microfluidic technique allows for direct integration of payloads into the PDMS microbeads. Specifically, we integrate an oxygen-sensitive porphyrin dye into the beads and show that the resulting structures can function as non-invasive and real-time oxygen microsensors utilizing a simple optical readout at the single-particle level. |
Databáze: | OpenAIRE |
Externí odkaz: |