Synthesis of N,N′-Dialkylated Cyclohexane-1,2-diamines and Their Application as Asymmetric Ligands and Organocatalysts for the Synthesis of Alcohols

Autor:	Suhyeon Kim, Euijin Shin, Valerii S. Kolesov, Tatyana V. Strelkova, Alexandra D. Samoylova, Ivan V. Fedyanin, Yuliya M. Kreschenova, S. E. Semenov, Jinho Oh, Fedor I. Zubkov, Alexey A. Tsygankov, Man-Seog Chun, Seongyeon Kwon, Denis Chusov
Rok vydání:	2016
Předmět:	chemistry.chemical_compound Cyclohexane 010405 organic chemistry Chemistry Organic Chemistry Organic chemistry Amine gas treating 010402 general chemistry 01 natural sciences 0104 chemical sciences
Zdroj:	Synlett. 28:615-619
ISSN:	1437-2096 0936-5214
DOI:	10.1055/s-0036-1588382
Popis:	A series of N,N′-dialkylated derivatives of (1R,2R)-cyclohexane-1,2-diamine were synthesized, and a new approach to the one-pot preparation of this type of amine was demonstrated. The prepared diamines were used as organocatalysts for the two-step synthesis of α-hydroxy γ-keto esters from arenes, chlorooxoacetates, and ketones; they were also used as chiral ligands for Meervein–Ponndorf–Verley reductions and Henry reactions.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a19eadf5eefee5110d9d1acc352baf6c https://doi.org/10.1055/s-0036-1588382 Zobrazit plný text záznamu