Biotransformations of α,β-Epoxyalcohols Catalyzed by Epoxide Hydrolases
Autor: | Moulay Abdelaziz Elalaoui, Tayeb Daiboun, Héalène Thaler-Dao, C. Chavis, Georges Maury |
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Rok vydání: | 1993 |
Předmět: | |
Zdroj: | Biocatalysis. 7:227-236 |
ISSN: | 0886-4454 |
DOI: | 10.3109/10242429308992096 |
Popis: | Microsomal and cytosolic fractions of mammalian livers were screened for their capacity to resolve racemic mixtures of trans -2,3-epoxy-l-alkanols. The epoxide hydrolase activities showed some specificity for the 2S, 3S enantiomers which were attacked at the proximate carbon atom. The best resolutions were observed with guinea pig liver microsomal enzymes. |
Databáze: | OpenAIRE |
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