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Maytenus emarginata (Willd.) Dind Hou belongs to family Celastraceae , is an evergreen tree that tolerates various types of stresses of the desert, loc ally known as “Kankero” . Maytenus emarginata has been used for fever, asthama, rheumatism and gastrointestinal disorders worldwide. The e ffect of alcoholic extract of leaves of Maytenus emarginata was investigated in rats to evaluate the anti - ulcer activity by using as pirin induced gastric ulcer pyloric ligation model. The parameters taken to assess anti - ulcer activity wer e volume of gastric secretion, p H, free acidity, total acidity and ulcer index. In present study the orally administered alcoholic extract significant ly ( P < 0.05 ) increases pH and decreases the vo lume of gastric acid secretion, free acidity, total acidity and ulcer index with respect to control at a dose of 125 and 187 mg/kg body weight . This study lend support to the traditional use of Maytenus emargi nata as antiulcerogenic. |
