Calcium Phosphate Nano-Composite with Bone Morphogenetic Protein
Autor: | SangCheol Moon, Jin Woo Lee, Kang Yong Lee, Min Park, Hwan Mo Lee, Hyun-Deuk Yochon-city Kim, Hyun Min Kim |
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Rok vydání: | 2007 |
Předmět: |
Nanocomposite
Materials science Mechanical Engineering Simulated body fluid Composite number Substrate (chemistry) chemistry.chemical_element engineering.material Calcium Phosphate Bone morphogenetic protein chemistry.chemical_compound Chemical engineering Coating chemistry Mechanics of Materials engineering General Materials Science |
Zdroj: | Key Engineering Materials. :361-364 |
ISSN: | 1662-9795 |
Popis: | Thick coatings of bone morphogenetic protein (BMP)-calcium phosphate nano-composite were prepared by a biomimetic process, in which substrates were immersed in modified simulated body fluid containing rh-BMP2 at room temperature and pressure. In vitro analyses showed that the calcium phosphate and BMP formed stable and uniform coating of composite on surface of substrate, and that the composite derive significant improvement in tissue formation, suggesting an osteoinductive bioactive surface. |
Databáze: | OpenAIRE |
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