Calcium Phosphate Nano-Composite with Bone Morphogenetic Protein

Autor: SangCheol Moon, Jin Woo Lee, Kang Yong Lee, Min Park, Hwan Mo Lee, Hyun-Deuk Yochon-city Kim, Hyun Min Kim
Rok vydání: 2007
Předmět:
Zdroj: Key Engineering Materials. :361-364
ISSN: 1662-9795
Popis: Thick coatings of bone morphogenetic protein (BMP)-calcium phosphate nano-composite were prepared by a biomimetic process, in which substrates were immersed in modified simulated body fluid containing rh-BMP2 at room temperature and pressure. In vitro analyses showed that the calcium phosphate and BMP formed stable and uniform coating of composite on surface of substrate, and that the composite derive significant improvement in tissue formation, suggesting an osteoinductive bioactive surface.
Databáze: OpenAIRE