Abstract 180: The Relation of Timing and Degree of Blood Pressure Control with Hematoma Growth - Secondary Analysis of The Interact2 Trial

Autor:	C. Stapf, E. Heeley, C. Delcourt, H. Arima, J. Chalmers, C. S Anderson
Rok vydání:	2014
Předmět:	Advanced and Specialized Nursing Neurology (clinical) Cardiology and Cardiovascular Medicine
Zdroj:	Stroke. 45
ISSN:	1524-4628 0039-2499
Popis:	Background: Acute blood pressure (BP) lowering therapy has shown clinical benefit in patients with acute intracerebral hemorrhage (ICH), but the effect of timing and degree of BP control on ICH growth has received less study. Methods: Among the INTERACT2 participants (N=2839) with acute ICH allocated either to intensive BP lowering therapy (IT, systolic target Results: Absolute mean ICH growth was lower in patients reaching BP target in 6h (4.6ml, p=0.04). Hematoma growth was particularly high (14.4ml, 95%CI:10.0-18.8) in patients admitted with systolic BP>160mmHg who achieved Conclusion: These findings suggest that early and sustained BP control have favorable effects on hematoma growth. This reinforces the principle for patients with acute ICH to receive BP lowering therapy as early as possible and to achieve a lower level of systolic BP for the most favorable outcome.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a15d04d8c66a505c5043dd671ce3b6e5 https://doi.org/10.1161/str.45.suppl_1.180 Zobrazit plný text záznamu